Deinococcus radiodurans is renowned for its extraordinary resistance to ionising radiation and other environmental stresses. This bacterium employs a combination of passive and active mechanisms to ...

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is ...

Cellular findings show Telomir-Zn modulates intracellular metal balance linked to oxidative stress, mitochondrial ...

Particle therapy, including proton and carbon ion radiotherapy, represents a major advancement in cancer treatment due to its ...

A clinical-stage oncology company developing targeted therapies that exploit DNA damage response (DDR) vulnerabilities in ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...

A major advance in cell biology has revealed how our cells safeguard their genetic material during one of the most vulnerable moments in their life cycle. The study identifies a specific protein ...

Three biochemical steps of the non-homologous DNA end-joining (NHEJ) process. This figure outlines the key stages of the NHEJ repair mechanism following DNA double-strand breaks. The process can be ...